STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iciAChromosome initiation inhibitor; Belongs to the LysR transcriptional regulatory family. (296 aa)    
Predicted Functional Partners:
PP_0916
Amino acid transporter LysE.
 
   
 0.941
dnaA
Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity).
    
 
 0.800
hda
Regulator of DnaA that prevents premature reinitiation of DNA replication; Function of homologous gene experimentally demonstrated in an other organism; putative transporter; DNA metabolism; Belongs to the DnaA family. HdA subfamily.
    
 
 0.752
PP_0918
Putative 3-beta hydroxysteroid dehydrogenase/isomerase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
     0.742
qseB
Two component system DNA-binding transcriptional activator QseB; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription.
      
 0.715
ihfB
Integration host factor subunit beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
      
 0.662
PP_0919
Homologs of previously reported genes of unknown function; Unknown function.
       0.608
sodB
Superoxide dismutase (Fe); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.
       0.606
lrp
DNA-binding transcriptional dual regulator, leucine-binding; Function of homologous gene experimentally demonstrated in an other organism; regulator; Aminoacidbiosynthesis : Pyruvate family.
   
  
 0.560
eda
KHG/KDPG aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Entner-Doudoroff.
      
 0.548
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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