STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumC-IFumarate hydratase (class 2); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (459 aa)    
Predicted Functional Partners:
PP_0897
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.981
sdhA
Succinate dehydrogenase flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 0.977
sdhB
Succinate dehydrogenase iron-sulfur subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic.
  
 0.961
sdhC
Succinate dehydrogenase membrane b-556 subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Aerobic.
   
 
 0.959
mdh
Putative malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
 0.957
sodA
Superoxide dismutase (Mn); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.949
maeB
Malic enzyme B; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.947
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
    
 0.932
mqo-III
Malate:quinone oxidoreductase; Function of strongly homologous gene; enzyme; Energymetabolism : TCA cycle.
  
 
 0.928
sdhD
Succinate dehydrogenase hydrophobic membrane anchor subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
   
 
 0.918
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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