STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsHPhosphocarrier protein HPr. (90 aa)    
Predicted Functional Partners:
fruB
Phosphotransferase system, fructose-specific EI/HPr/EIIA components; Function experimentally demonstrated in the studied genus; transporter; Energymetabolism : Sugars; Belongs to the PEP-utilizing enzyme family.
 
 0.999
fruA
Fructose PTS permease - IIBC component; Function of homologous gene experimentally demonstrated in an other organism; transporter; Energy metabolism.
  
 
 0.985
ptsN
Phosphotransferase system enzyme IIA, regulation of potassium transport; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transportandbindingproteins : Carbohydrates, organic alcohols, and acids.
 
  
 0.956
ptsP
Phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins); Function of homologous gene experimentally demonstrated in an other organism; regulator; Energy metabolism; Belongs to the PEP-utilizing enzyme family.
  
 
 
 0.951
PP_0949
Putative ATP-binding protein UPF0042; Displays ATPase and GTPase activities.
  
  
 0.857
hpf
Ribosome hibernation promoting factor; During stationary phase, promotes and stabilizes dimerization of 70S ribosomes by the ribosome modulation factor (RMF), leading to the formation of inactive 100S ribosomes. Belongs to the HPF/YfiA ribosome-associated protein family. Short HPF subfamily.
  
  
 0.814
PP_0728
Homologs of previously reported genes of unknown function.
  
 
 0.801
rbsR
DNA-binding transcriptional repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator; Purines,pyrimidines,nucleosides,andnucleotides : Nucleotide and nucleoside interconversions.
  
 
 0.793
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the xylCAB operon and the xylS gene. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein XylR for the expression of the xylCAB operon and xylS.
 
  
 0.771
lptA
Conserved exported protein of unknown function; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
  
  
 0.761
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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