STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_0973Nucleoid-associated protein PP_0973. (335 aa)    
Predicted Functional Partners:
ygiF
Putative thiamine triphosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Purines, pyrimidines, nucleosides, and nucleotides.
  
   
 0.809
evgA
DNA-binding response regulator in two-component regulatory system with EvgS; Function of homologous gene experimentally demonstrated in an other organism; regulator.
      
 0.758
trmE
GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
  
  
 0.728
PP_1523
Homologs of previously reported genes of unknown function.
 
     0.633
sdhE
Conserved protein of unknown function, DUF339 family; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinyl [...]
  
     0.595
yohC
Putative inner membrane protein of unknown function; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component; Transport and binding proteins.
  
     0.593
PP_4954
Homologs of previously reported genes of unknown function.
  
     0.592
sixA
Phosphohistidine phosphatase SixA.
 
    0.578
PP_2187
Universal stress protein family.
  
     0.577
PP_2745
Universal stress protein family.
  
     0.573
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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