Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_0994Putative RNA polymerase sigma factor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the sigma-70 factor family. ECF subfamily. (178 aa)    
Predicted Functional Partners:
PP_0995
Homologs of previously reported genes of unknown function.
 
  
 0.995
sstT
Serine/threonine transporter SstT; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
      
 0.768
mucA
Sigma factor AlgU negative regulatory protein.
  
 
 0.631
PP_2888
Putative ECF sigma factor PrtI; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.574
PP_0993
Homologs of previously reported genes of unknown function.
  
    0.563
PP_2889
Putative Transmembrane regulator PrtR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.550
PP_0991
Homologs of previously reported genes of unknown function.
  
    0.526
PP_0990
DoxX family protein.
 
  
 0.498
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the xylCAB operon and the xylS gene. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein XylR for the expression of the xylCAB operon and xylS.
   
  
 0.478
greB
Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.
     
 0.469
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.