| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_3556 | gltS | PP_3556 | PP_0996 | Homologs of previously reported genes of unknown function. | Glutamate:sodium symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family. | 0.528 |
| PP_3954 | gltS | PP_3954 | PP_0996 | Periplasmic binding subunit of unknown solute; Function of strongly homologous gene; transporter. | Glutamate:sodium symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family. | 0.836 |
| eda | edd | PP_1024 | PP_1010 | KHG/KDPG aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Entner-Doudoroff. | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.999 |
| eda | glk | PP_1024 | PP_1011 | KHG/KDPG aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Entner-Doudoroff. | Glucokinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the bacterial glucokinase family. | 0.991 |
| eda | gltS | PP_1024 | PP_0996 | KHG/KDPG aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Entner-Doudoroff. | Glutamate:sodium symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family. | 0.762 |
| eda | hexR | PP_1024 | PP_1021 | KHG/KDPG aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Entner-Doudoroff. | DNA-binding transcriptional regulator; Involved in regulation of glucose metabolism. Transcriptional repressor of the gap-1 gene and of the edd-glk-gltR-2 and zwf-pgl-eda operons. Acts by binding directly to an inverted pseudopalindromic sequence in the promoter region. | 0.964 |
| eda | ptxS | PP_1024 | PP_3380 | KHG/KDPG aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Entner-Doudoroff. | 2-ketogluconate utilization repressor; Function experimentally demonstrated in the studied genus; regulator; Biologicalprocesses : Control. | 0.603 |
| eda | zwf | PP_1024 | PP_5351 | KHG/KDPG aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Entner-Doudoroff. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.948 |
| eda | zwfA | PP_1024 | PP_1022 | KHG/KDPG aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Entner-Doudoroff. | Glucose 6-phosphate-1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.988 |
| eda | zwfB | PP_1024 | PP_4042 | KHG/KDPG aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Entner-Doudoroff. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.942 |
| edd | eda | PP_1010 | PP_1024 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | KHG/KDPG aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Entner-Doudoroff. | 0.999 |
| edd | glk | PP_1010 | PP_1011 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Glucokinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the bacterial glucokinase family. | 0.992 |
| edd | gltS | PP_1010 | PP_0996 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Glutamate:sodium symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family. | 0.667 |
| edd | hexR | PP_1010 | PP_1021 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | DNA-binding transcriptional regulator; Involved in regulation of glucose metabolism. Transcriptional repressor of the gap-1 gene and of the edd-glk-gltR-2 and zwf-pgl-eda operons. Acts by binding directly to an inverted pseudopalindromic sequence in the promoter region. | 0.913 |
| edd | ptxS | PP_1010 | PP_3380 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 2-ketogluconate utilization repressor; Function experimentally demonstrated in the studied genus; regulator; Biologicalprocesses : Control. | 0.639 |
| edd | zwf | PP_1010 | PP_5351 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.968 |
| edd | zwfA | PP_1010 | PP_1022 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Glucose 6-phosphate-1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.972 |
| edd | zwfB | PP_1010 | PP_4042 | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.961 |
| glk | eda | PP_1011 | PP_1024 | Glucokinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the bacterial glucokinase family. | KHG/KDPG aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Entner-Doudoroff. | 0.991 |
| glk | edd | PP_1011 | PP_1010 | Glucokinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the bacterial glucokinase family. | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.992 |