Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PP_0997Sigma-54 dependent transcriptional regulator/sensory box protein. (502 aa)    
Predicted Functional Partners:
arcD-I
Arginine/ornithine antiporter; Function experimentally demonstrated in the studied genus; transporter; Transport and binding proteins.
     
 0.800
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the xylCAB operon and the xylS gene. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein XylR for the expression of the xylCAB operon and xylS.
  
   
 0.780
arcC
Carbamate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family; Belongs to the carbamate kinase family.
     
 0.780
PP_0998
Homologs of previously reported genes of unknown function.
       0.725
gcvH-I
Glycine cleavage system H protein 1; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
     
 0.627
arcA
Arginine deiminase; Function experimentally demonstrated in the studied species; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
     
 0.521
gcvT-I
Aminomethyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Centralintermediarymetabolism : One-carbon metabolism.
     
 0.506
gltS
Glutamate:sodium symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
       0.497
urtA
Putative Urea ABC transporter, periplasmic protein; Function of homologous gene experimentally demonstrated in an other organism; putative transporter; Transport and binding proteins.
 
      0.416
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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