Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_1026Peptidase, M23/M37 family. (275 aa)    
Predicted Functional Partners:
xseA
Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
       0.869
PP_5057
Peptidase, M23/M37 family.
 
   
 0.784
PP_1029
Homologs of previously reported genes of unknown function.
       0.675
PP_1030
Homologs of previously reported genes of unknown function.
       0.642
guaB
IMP dehydrogenase and single strand DNA binding factor; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.604
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
       0.581
mrcA
Penicillin-insensitive transglycosylase/penicillin-sensitive transpeptidase; Function of strongly homologous gene; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan.
 
   
 0.578
amiC
N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of murein sacculus and peptidoglycan.
 
   
 0.571
ftsX
Membrane component of the ABC transporter FtsEX involved in cellular division; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
  
 0.557
PP_1028
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
       0.555
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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