Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_1029Homologs of previously reported genes of unknown function. (251 aa)    
Predicted Functional Partners:
PP_1030
Homologs of previously reported genes of unknown function.
       0.716
PP_1026
Peptidase, M23/M37 family.
       0.675
xseA
Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
       0.675
PP_1028
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
       0.569
PP_3247
Transporter, bile acid/Na+ symporter family.
  
    0.518
guaB
IMP dehydrogenase and single strand DNA binding factor; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.495
PP_0830
Acetyltransferase, GNAT family.
 
     0.435
PP_3543
Iron-sulfur cluster-binding protein.
   
    0.418
PP_4259
Iron-sulfur cluster-binding protein.
   
    0.418
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.416
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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