STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_1061Putative ATP-dependent DNA helicase lhr; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (1434 aa)    
Predicted Functional Partners:
PP_1060
Putative Glutamate synthase, large subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the glutamate synthase family.
     
 0.906
PP_3350
Homologs of previously reported genes of unknown function.
  
   
 0.861
PP_5245
Transcriptional regulator, AraC family.
      
 0.835
kefB-III
Glutathione-regulated potassium/H+ antiporter; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Cations and iron carrying compounds; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
      
 0.835
wbpL
Glycosyl transferase WbpL.
  
   
 0.778
ttgB
Probable efflux pump membrane transporter TtgB; Probable membrane transporter component of the TtgABC efflux pump with unknown specificity; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
      
 0.646
mutM
Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 0.571
PP_1062
MutT/nudix family protein; Belongs to the Nudix hydrolase family.
       0.551
PP_3235
Homologs of previously reported genes of unknown function.
  
    0.510
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
      
 0.489
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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