STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_1064Hydrolase, alpha/beta fold family. (378 aa)    
Predicted Functional Partners:
metR-I
DNA-binding transcriptional regulator, homocysteine-binding; Function of homologous gene experimentally demonstrated in an other organism; regulator; Aminoacidbiosynthesis : Aspartate family; Belongs to the LysR transcriptional regulatory family.
       0.639
ethA
FAD-containing monooxygenase EthA; Catalyzes a Baeyer-Villiger oxidation reaction, i.e. the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters or lactones using NADPH and/or NADH as an electron donor. Preferentially converts short-chain aliphatic ketones like 2-decanone, 3-decanone and 4-decanone. Some acyclic ketones are converted not only to the alkylacetates, but also methyl- and ethylesters are obtained, indicating insertion of oxygen on both sides of the keto group; Belongs to the FAD-binding monooxygenase family.
 
 
 0.596
PP_4540
Hydrolase, alpha/beta fold family.
  
   
 0.538
PP_1950
Homologs of previously reported genes of unknown function; Belongs to the cytochrome P450 family.
 
 0.491
PP_3645
Putative L-proline amide hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Biologicalprocesses : Scavenge (Catabolism).
  
   
 0.484
PP_4624
Putative hydrolase, alpha/beta fold family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity.
  
     0.479
PP_1955
Cytochrome P450 family protein.
 
 0.468
PP_3505
Homologs of previously reported genes of unknown function.
 
  
 0.450
PP_2437
Putative Acyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  0.443
PP_2308
Putative Acyl-CoA thioesterase II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
  0.433
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.