Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dctD-IIC4-dicarboxylate transport transcriptional regulatory protein; Function of strongly homologous gene; regulator. (442 aa)    
Predicted Functional Partners:
PP_1067
Sensor histidine kinase.
 0.999
PP_3552
Sensory box histidine kinase.
 
 
 0.980
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the xylCAB operon and the xylS gene. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein XylR for the expression of the xylCAB operon and xylS.
 
   
 0.792
PP_0264
Sensor histidine kinase.
 
 0.749
dctB
C4-dicarboxylate transport sensor protein.
 
 0.734
glmP
Membrane protein required for efficient alginate biosynthesis; Function of strongly homologous gene; Unknown function.
       0.712
PP_4959
Diguanylate cyclase; Function of strongly homologous gene; enzyme.
  
 
 0.604
gltL
Glutamate / aspartate ABC transporter - ATP binding subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Aminoacidbiosynthesis : Aspartate family.
  
    0.593
glnL
Two-component system sensory histidine kinase/phosphatase GlnL/GlnG; Function of homologous gene experimentally demonstrated in an other organism; receptor; Centralintermediarymetabolism : Nitrogen metabolism.
 
 0.590
gltJ
Glutamate / aspartate ABC transporter - permease subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Aminoacidbiosynthesis : Aspartate family.
  
    0.587
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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