Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
grxDMonothiol glutaredoxin 4; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Electron transport; Belongs to the glutaredoxin family. Monothiol subfamily. (111 aa)    
Predicted Functional Partners:
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 0.952
bolA
DNA-binding transcriptional dual regulator; Function of homologous gene experimentally demonstrated in an other organism; regulator; Regulatory functions; Belongs to the BolA/IbaG family.
 
 
 0.901
tsaA
Putative peroxiredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.846
ygiF
Putative thiamine triphosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Purines, pyrimidines, nucleosides, and nucleotides.
      
 0.768
grxC
Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
 
 
 0.740
dps
DNA-binding stress protein; Function experimentally demonstrated in the studied species; enzyme; DNAmetabolism : Chromosome-associated proteins; Belongs to the Dps family.
   
  
 0.716
ttg2F
Putative BolA family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the BolA/IbaG family.
 
 
 
 0.692
erpA
Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG.
 
 0.686
ubiH
2-octaprenyl-6-methoxyphenyl hydroxylase.
  
    0.684
grx
Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
 
 
 0.671
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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