STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tsaAPutative peroxiredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (200 aa)    
Predicted Functional Partners:
dps
DNA-binding stress protein; Function experimentally demonstrated in the studied species; enzyme; DNAmetabolism : Chromosome-associated proteins; Belongs to the Dps family.
  
  
 0.880
grxD
Monothiol glutaredoxin 4; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Electron transport; Belongs to the glutaredoxin family. Monothiol subfamily.
  
 
 0.846
trxB
Thioredoxin reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism.
  
 
 0.833
ahpF
Alkyl hydroperoxide reductase subunit F; Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein (By similarity); Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
  
  
 0.831
ohr
Organic hydroperoxide resistance protein.
      
 0.710
PP_2700
AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.710
PP_1235
AhpC/TSA family protein.
 
 
 0.673
oprE
Outer-membrane porin E; Function experimentally demonstrated in the studied genus; transporter; Transportandbindingproteins : Porins.
      
 0.655
stcD
Putative N-methylproline demethylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.628
sodB
Superoxide dismutase (Fe); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.621
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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