node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PP_1102 | PP_1103 | PP_1102 | PP_1103 | Homologs of previously reported genes of unknown function. | ATP-dependent helicase, DEAD box family. | 0.956 |
PP_1102 | PP_1105 | PP_1102 | PP_1105 | Homologs of previously reported genes of unknown function. | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.979 |
PP_1102 | PP_1106 | PP_1102 | PP_1106 | Homologs of previously reported genes of unknown function. | Homologs of previously reported genes of unknown function. | 0.880 |
PP_1102 | sbcD | PP_1102 | PP_2025 | Homologs of previously reported genes of unknown function. | Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.740 |
PP_1103 | PP_1102 | PP_1103 | PP_1102 | ATP-dependent helicase, DEAD box family. | Homologs of previously reported genes of unknown function. | 0.956 |
PP_1103 | PP_1105 | PP_1103 | PP_1105 | ATP-dependent helicase, DEAD box family. | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.871 |
PP_1103 | PP_1106 | PP_1103 | PP_1106 | ATP-dependent helicase, DEAD box family. | Homologs of previously reported genes of unknown function. | 0.872 |
PP_1105 | PP_1102 | PP_1105 | PP_1102 | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Homologs of previously reported genes of unknown function. | 0.979 |
PP_1105 | PP_1103 | PP_1105 | PP_1103 | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | ATP-dependent helicase, DEAD box family. | 0.871 |
PP_1105 | PP_1106 | PP_1105 | PP_1106 | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Homologs of previously reported genes of unknown function. | 0.996 |
PP_1105 | dnaN | PP_1105 | PP_0011 | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.913 |
PP_1105 | imuB | PP_1105 | PP_3118 | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | DNA linked enzyme involved in DNA repair; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.767 |
PP_1105 | ligA | PP_1105 | PP_4274 | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.911 |
PP_1105 | ligB | PP_1105 | PP_4968 | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | DNA ligase B; Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily. | 0.911 |
PP_1105 | polA | PP_1105 | PP_0123 | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | DNA polymerase I, 5' -> 3' polymerase with 5' --> 3' and 3' --> 5' exonuclease activity; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.837 |
PP_1105 | recD | PP_1105 | PP_4672 | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | ATP-dependent DNA helicase and dsDNA/ssDNA exonuclease, ssDNA endonuclease; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA f [...] | 0.742 |
PP_1105 | sbcD | PP_1105 | PP_2025 | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.931 |
PP_1106 | PP_1102 | PP_1106 | PP_1102 | Homologs of previously reported genes of unknown function. | Homologs of previously reported genes of unknown function. | 0.880 |
PP_1106 | PP_1103 | PP_1106 | PP_1103 | Homologs of previously reported genes of unknown function. | ATP-dependent helicase, DEAD box family. | 0.872 |
PP_1106 | PP_1105 | PP_1106 | PP_1105 | Homologs of previously reported genes of unknown function. | Putative DNA ligase, ATP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.996 |