STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
PP_1111Putative Synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (262 aa)    
Predicted Functional Partners:
PP_1110
Serine acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Serine family.
  
    0.842
PP_1113
Pyridoxal-phosphate dependent enzyme family protein.
  
    0.813
PP_1112
Homologs of previously reported genes of unknown function.
  
    0.789
relA
ATP:GTP 3'-pyrophosphotransferase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
      
 0.651
nth
DNA glycosylase/apyrimidinic (AP) lyase specific for damaged pyrimidinic sites; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
     0.539
PP_1109
Transcriptional regulator, GntR family.
       0.514
PP_3807
Thioesterase.
     
 0.502
PP_4247
Exonuclease.
    
   0.451
spuB
Glutamylpolyamine synthetase; Function experimentally demonstrated in the studied genus; enzyme; Centralintermediarymetabolism : Polyamine biosynthesis; Belongs to the glutamine synthetase family.
  
  
 0.432
puuA-I
Glutamate-putrescine ligase; Function experimentally demonstrated in the studied genus; enzyme; Central intermediary metabolism; Belongs to the glutamine synthetase family.
     
 0.430
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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