STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_1126Putative Hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (782 aa)    
Predicted Functional Partners:
dinG
Putative Helicase; DNA-dependent ATPase and 5'-3' DNA helicase.
  
    0.774
algK
Alginate biosynthesis protein AlgK; May be involved in the polymerization of mannuronate to alginate.
  
     0.762
algX
Alginate biosynthesis protein AlgX; Plays two roles in the biosynthesis of the exopolysaccharide alginate: protects alginate from degradation as the polymer traverses the periplasm, and also plays a role in its O-acetylation. Probably has acetyltransferase activity in vivo (By similarity).
  
     0.758
bglX
Periplasmic beta-D-glucoside glucohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the glycosyl hydrolase 3 family.
     
 0.736
PP_0149
Homologs of previously reported genes of unknown function.
  
    0.720
estC
Carboxylesterase.
 
    0.719
PP_2852
Putative Sulfatase domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.699
algJ
Probable alginate O-acetylase AlgJ; Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization-transport complex and adds acetyl groups at the O-2 and O-3 positions of mannuronate residues. Acetylation of alginate is important for the architecture of biofilms and increases the ability of alginate to act as a defense barrier (By similarity).
  
     0.689
PP_1666
Homologs of previously reported genes of unknown function.
  
     0.667
PP_0330
Hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.650
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.