Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_1165Homologs of previously reported genes of unknown function. (289 aa)    
Predicted Functional Partners:
glk
Glucokinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the bacterial glucokinase family.
    
 0.916
PP_1166
Putative permease of the drug/metabolite transporter (DMT) superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Transport and binding proteins.
     
 0.765
PP_3394
Putative 3-hydroxy-3-methylglutaryl-CoA lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the alpha-IPM synthase/homocitrate synthase family.
      
 0.762
fbpA
Putative iron(III)|iron ABC transporter, periplasmic iron-binding protein; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Cations and iron carrying compounds.
      
 0.762
mvaB
Hydroxymethylglutaryl-CoA lyase.
      
 0.754
gnl
Gluconolactonase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars.
 
  
 0.737
bcsZ
endo-1,4-D-glucanase subunit of cellulose synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Biosynthesis and degradation of polysaccharides; Belongs to the glycosyl hydrolase 8 (cellulase D) family.
  
   
 0.680
PP_1167
Putative TRAP dicarboxylate transporter, DctM subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.577
PP_2744
Ribose-phosphate pyrophosphokinase family protein.
      
 0.575
birA
Bifunctional biotin-[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
      
 0.573
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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