STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kupProbable potassium transport system protein kup; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family. (636 aa)    
Predicted Functional Partners:
PP_5355
Putative Sodium/proton antiporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
   
 0.868
cvrA
K(+)/H(+) antiporter NhaP2; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
      
 0.785
kdpC
Potassium-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
  
  
 0.761
PP_2938
Homologs of previously reported genes of unknown function.
      
 0.741
PP_1198
Transcriptional regulator, Cro/CI family (higA antitoxin like); Function of strongly homologous gene; regulator; Cellularprocesses : Toxin production and resistance.
      
 0.738
PP_1717
Homologs of previously reported genes of unknown function.
      
 0.737
kdpA
Potassium-transporting ATPase A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.
   
  
 0.680
PP_0274
Putative transcriptional regulator containing HTH domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions.
      
 0.649
PP_1716
Transcriptional regulator, Cro/CI family.
      
 0.649
PP_2499
Homologs of previously reported genes of unknown function.
      
 0.649
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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