Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_1248Transporter, LysE family. (255 aa)    
Predicted Functional Partners:
carA
Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.
  
    0.883
PP_2388
Transporter, LysE family.
 
    0.786
PP_3653
Transporter, LysE family.
  
     0.774
carB
Carbamoyl-phosphate synthase large chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family.
  
  
 0.757
PP_3021
Transporter, LysE family.
  
     0.739
PP_1249
Conserved protein of unknown function, DUF4223 family; Homologs of previously reported genes of unknown function; Unknown function.
  
    0.585
PP_4721
Homologs of previously reported genes of unknown function.
       0.488
greA
Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
       0.488
PP_2039
Putative Acyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
      
 0.480
PP_3492
Short-chain acyl-CoA dehydrogenase; Function of strongly homologous gene; enzyme.
      
 0.480
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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