| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_1255 | PP_1256 | PP_1255 | PP_1256 | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | Putative alpha-ketoglutarate semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Amino acids and amines. | 0.858 |
| PP_1255 | PP_1257 | PP_1255 | PP_1257 | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. | 0.974 |
| PP_1255 | PP_3190 | PP_1255 | PP_3190 | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | Ornithine cyclodeaminase/mu-crystallin family protein. | 0.487 |
| PP_1255 | PP_4452 | PP_1255 | PP_4452 | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | NAD/NADP octopine/nopaline dehydrogenase family protein. | 0.704 |
| PP_1255 | dadX | PP_1255 | PP_5269 | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | Alanine racemase, PLP-binding; Isomerizes L-alanine to D-alanine which is then likely oxidized to pyruvate by DadA. Shows racemase activity with both alanine stereoisomers, negligible activity with D-cysteine and L-serine, and exhibits no activity with the remaining natural chiral amino acids. | 0.500 |
| PP_1255 | ocd | PP_1255 | PP_4431 | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | Ornithine cyclodeaminase 1. | 0.487 |
| PP_1255 | ooxA | PP_1255 | PP_4456 | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | Opine oxidase subunit A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines. | 0.966 |
| PP_1255 | ooxB | PP_1255 | PP_4457 | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | Opine oxidase subunit B; Function of strongly homologous gene; enzyme; Energymetabolism : Amino acids and amines. | 0.954 |
| PP_1255 | prpA | PP_1255 | PP_1258 | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | 4-hydroxyproline epimerase; Catalyzes the reversible epimerization of cis-4-hydroxy-D- proline (c4DHyp) to trans-4-hydroxy-L-proline (t4LHyp). May be involved in a degradation pathway that allows P.putida strain KT2440 to grow on either epimer of 4-hydroxyproline, c4DHyp and t4LHyp, as the sole carbon and nitrogen source. Does not exhibit measureable racemase activity in vitro with any of the 19 natural chiral amino acid enantiomers. | 0.983 |
| PP_1255 | soxA | PP_1255 | PP_0325 | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | Sarcosine oxidase subunit alpha; Function experimentally demonstrated in the studied genus; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the GcvT family. | 0.729 |
| PP_1256 | PP_1255 | PP_1256 | PP_1255 | Putative alpha-ketoglutarate semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Amino acids and amines. | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | 0.858 |
| PP_1256 | PP_1257 | PP_1256 | PP_1257 | Putative alpha-ketoglutarate semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Amino acids and amines. | Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. | 0.982 |
| PP_1256 | prpA | PP_1256 | PP_1258 | Putative alpha-ketoglutarate semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Amino acids and amines. | 4-hydroxyproline epimerase; Catalyzes the reversible epimerization of cis-4-hydroxy-D- proline (c4DHyp) to trans-4-hydroxy-L-proline (t4LHyp). May be involved in a degradation pathway that allows P.putida strain KT2440 to grow on either epimer of 4-hydroxyproline, c4DHyp and t4LHyp, as the sole carbon and nitrogen source. Does not exhibit measureable racemase activity in vitro with any of the 19 natural chiral amino acid enantiomers. | 0.959 |
| PP_1257 | PP_1255 | PP_1257 | PP_1255 | Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | 0.974 |
| PP_1257 | PP_1256 | PP_1257 | PP_1256 | Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. | Putative alpha-ketoglutarate semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Amino acids and amines. | 0.982 |
| PP_1257 | prpA | PP_1257 | PP_1258 | Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. | 4-hydroxyproline epimerase; Catalyzes the reversible epimerization of cis-4-hydroxy-D- proline (c4DHyp) to trans-4-hydroxy-L-proline (t4LHyp). May be involved in a degradation pathway that allows P.putida strain KT2440 to grow on either epimer of 4-hydroxyproline, c4DHyp and t4LHyp, as the sole carbon and nitrogen source. Does not exhibit measureable racemase activity in vitro with any of the 19 natural chiral amino acid enantiomers. | 0.917 |
| PP_3190 | PP_1255 | PP_3190 | PP_1255 | Ornithine cyclodeaminase/mu-crystallin family protein. | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | 0.487 |
| PP_3190 | ocd | PP_3190 | PP_4431 | Ornithine cyclodeaminase/mu-crystallin family protein. | Ornithine cyclodeaminase 1. | 0.914 |
| PP_3190 | ooxA | PP_3190 | PP_4456 | Ornithine cyclodeaminase/mu-crystallin family protein. | Opine oxidase subunit A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines. | 0.769 |
| PP_3190 | ooxB | PP_3190 | PP_4457 | Ornithine cyclodeaminase/mu-crystallin family protein. | Opine oxidase subunit B; Function of strongly homologous gene; enzyme; Energymetabolism : Amino acids and amines. | 0.815 |