| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_1255 | PP_1256 | PP_1255 | PP_1256 | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | Putative alpha-ketoglutarate semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Amino acids and amines. | 0.855 |
| PP_1255 | PP_1257 | PP_1255 | PP_1257 | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. | 0.974 |
| PP_1255 | prpA | PP_1255 | PP_1258 | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | 4-hydroxyproline epimerase; Catalyzes the reversible epimerization of cis-4-hydroxy-D- proline (c4DHyp) to trans-4-hydroxy-L-proline (t4LHyp). May be involved in a degradation pathway that allows P.putida strain KT2440 to grow on either epimer of 4-hydroxyproline, c4DHyp and t4LHyp, as the sole carbon and nitrogen source. Does not exhibit measureable racemase activity in vitro with any of the 19 natural chiral amino acid enantiomers. | 0.983 |
| PP_1256 | PP_1255 | PP_1256 | PP_1255 | Putative alpha-ketoglutarate semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Amino acids and amines. | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | 0.855 |
| PP_1256 | PP_1257 | PP_1256 | PP_1257 | Putative alpha-ketoglutarate semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Amino acids and amines. | Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. | 0.996 |
| PP_1256 | PP_2585 | PP_1256 | PP_2585 | Putative alpha-ketoglutarate semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Amino acids and amines. | Alpha-ketoglutaric semialdehyde dehydrogenase. | 0.904 |
| PP_1256 | PP_3602 | PP_1256 | PP_3602 | Putative alpha-ketoglutarate semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Amino acids and amines. | 2,5-dioxovalerate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. | 0.904 |
| PP_1256 | dpkA | PP_1256 | PP_3591 | Putative alpha-ketoglutarate semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Amino acids and amines. | Delta 1-piperideine-2-carboxylate reductase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Amino acids and amines; Belongs to the LDH2/MDH2 oxidoreductase family. | 0.457 |
| PP_1256 | prpA | PP_1256 | PP_1258 | Putative alpha-ketoglutarate semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Amino acids and amines. | 4-hydroxyproline epimerase; Catalyzes the reversible epimerization of cis-4-hydroxy-D- proline (c4DHyp) to trans-4-hydroxy-L-proline (t4LHyp). May be involved in a degradation pathway that allows P.putida strain KT2440 to grow on either epimer of 4-hydroxyproline, c4DHyp and t4LHyp, as the sole carbon and nitrogen source. Does not exhibit measureable racemase activity in vitro with any of the 19 natural chiral amino acid enantiomers. | 0.976 |
| PP_1257 | PP_1255 | PP_1257 | PP_1255 | Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. | Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines. | 0.974 |
| PP_1257 | PP_1256 | PP_1257 | PP_1256 | Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. | Putative alpha-ketoglutarate semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Amino acids and amines. | 0.996 |
| PP_1257 | PP_2585 | PP_1257 | PP_2585 | Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. | Alpha-ketoglutaric semialdehyde dehydrogenase. | 0.993 |
| PP_1257 | PP_3602 | PP_1257 | PP_3602 | Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. | 2,5-dioxovalerate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism. | 0.993 |
| PP_1257 | dpkA | PP_1257 | PP_3591 | Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. | Delta 1-piperideine-2-carboxylate reductase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Amino acids and amines; Belongs to the LDH2/MDH2 oxidoreductase family. | 0.462 |
| PP_1257 | gatC | PP_1257 | PP_0932 | Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | 0.484 |
| PP_1257 | pheA | PP_1257 | PP_1769 | Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. | Chorismate mutase/Prephenate dehydratase; Function of strongly homologous gene; enzyme. | 0.562 |
| PP_1257 | prpA | PP_1257 | PP_1258 | Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. | 4-hydroxyproline epimerase; Catalyzes the reversible epimerization of cis-4-hydroxy-D- proline (c4DHyp) to trans-4-hydroxy-L-proline (t4LHyp). May be involved in a degradation pathway that allows P.putida strain KT2440 to grow on either epimer of 4-hydroxyproline, c4DHyp and t4LHyp, as the sole carbon and nitrogen source. Does not exhibit measureable racemase activity in vitro with any of the 19 natural chiral amino acid enantiomers. | 0.986 |
| PP_1257 | rpsO | PP_1257 | PP_4709 | Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. | 30S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.446 |
| PP_1257 | yveA | PP_1257 | PP_1259 | Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. | Aspartate-proton symporter. | 0.592 |
| PP_2585 | PP_1256 | PP_2585 | PP_1256 | Alpha-ketoglutaric semialdehyde dehydrogenase. | Putative alpha-ketoglutarate semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Amino acids and amines. | 0.904 |