STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_1257Putative 1-pyrroline-4-hydroxy-2-carboxylate deaminase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines; Belongs to the DapA family. (315 aa)    
Predicted Functional Partners:
PP_1256
Putative alpha-ketoglutarate semialdehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Energymetabolism : Amino acids and amines.
 
 
 0.982
PP_1255
Putative cis-4-hydroxy-D-proline oxidase; No homology to any previously reported sequences; putative enzyme; Energymetabolism : Amino acids and amines.
 
 
 0.974
PP_3602
2,5-dioxovalerate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism.
 
 
 0.963
PP_2585
Alpha-ketoglutaric semialdehyde dehydrogenase.
 
 
 0.962
prpA
4-hydroxyproline epimerase; Catalyzes the reversible epimerization of cis-4-hydroxy-D- proline (c4DHyp) to trans-4-hydroxy-L-proline (t4LHyp). May be involved in a degradation pathway that allows P.putida strain KT2440 to grow on either epimer of 4-hydroxyproline, c4DHyp and t4LHyp, as the sole carbon and nitrogen source. Does not exhibit measureable racemase activity in vitro with any of the 19 natural chiral amino acid enantiomers.
 
  
 0.917
yveA
Aspartate-proton symporter.
     
 0.595
dapB
4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
 
  
 0.583
pheA
Chorismate mutase/Prephenate dehydratase; Function of strongly homologous gene; enzyme.
  
  
 0.578
gatC
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.
  
  
 0.520
dpkA
Delta 1-piperideine-2-carboxylate reductase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Amino acids and amines; Belongs to the LDH2/MDH2 oxidoreductase family.
 
   
 0.475
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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