Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ghrB2-ketoaldonate reductase / hydroxypyruvate/glyoxylate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (324 aa)    
Predicted Functional Partners:
kguK
Putative 2-ketogluconokinase; Function experimentally demonstrated in the studied genus; putative enzyme; Energy metabolism.
 
 
 0.962
ttuD
Putative hydroxypyruvate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 0.942
glcD
Glycolate oxidase, putative FAD-linked subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
 
 
 0.927
hprA
Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 
0.925
glcE
Glycolate oxidase, putative FAD-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism.
 
 
 0.922
garK
Glycerate kinase; Function experimentally demonstrated in the studied strain; enzyme; Energymetabolism : Sugars; Belongs to the glycerate kinase type-1 family.
 
  
 0.921
gloA
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
   
 0.913
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 
 0.910
PP_3384
Gluconate 2-dehydrogenase gamma subunit; Function of strongly homologous gene; enzyme; Energy metabolism.
  
 
 0.909
hyi
Hydroxypyruvate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism; Belongs to the hyi family.
   
 
 0.906
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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