STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhaVToxin endoribonuclease of toxin antitoxin system SohB(PrlF)-YhaV; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Transcription. (155 aa)    
Predicted Functional Partners:
PP_1268
Putative HtrA suppressor protein sohA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.989
mqsR
Motility quorum-sensing regulator / GCU-specific mRNA interferase toxin; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription : Degradation of RNA.
   
  
 0.883
yoeB
Toxin of the YefM-YoeB antitoxin/toxin complex and DNA-binding transcriptional repressor; Function of homologous gene experimentally demonstrated in an other organism; factor; Cellularprocesses : Toxin production and resistance.
  
  
 0.874
PP_1269
Universal stress protein family.
       0.682
lon-II
DNA-binding, ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
   
  
 0.652
lon-I
DNA-binding, ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
   
  
 0.648
PP_5435
Homologs of previously reported genes of unknown function; Unknown function.
     
 0.444
relA
ATP:GTP 3'-pyrophosphotransferase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
      
 0.436
yefM
Antitoxin of the YoeB-YefM toxin-antitoxin pair and DNA binding transcriptional repressor; Antitoxin component of a type II toxin-antitoxin (TA) system.
  
  
 0.430
PP_3315
Homologs of previously reported genes of unknown function.
  
     0.403
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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