Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_1274Oxidoreductase, short-chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (270 aa)    
Predicted Functional Partners:
PP_1951
Oxidoreductase, short chain dehydrogenase/reductase family.
  
 
   0.755
PP_1275
Homologs of previously reported genes of unknown function.
       0.680
PP_2002
Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
   0.626
yciK
Putative oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Fattyacidandphospholipidmetabolism : Biosynthesis.
  
   0.540
PP_1817
Oxidoreductase, short-chain dehydrogenase/reductase family.
 
 
  
0.534
PP_3547
Putative NAD(P)-binding oxidoreductase with NAD(P)-binding Rossmann-fold domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity.
  
 
   0.532
PP_4616
Homologs of previously reported genes of unknown function.
 
      0.504
PP_2175
Putative 3-oxoacyl-(Acyl-carrier-protein) reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
   0.483
PP_2881
Oxidoreductase, short chain dehydrogenase/reductase family.
 
     0.462
sucC
succinyl-CoA synthetase, beta subunit glutaryl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
 0.460
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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