node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PP_2124 | PP_3142 | PP_2124 | PP_3142 | Putative Glycosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Putative Sugar transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.679 |
PP_2124 | algA | PP_2124 | PP_1277 | Putative Glycosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity). | 0.951 |
PP_2124 | algD | PP_2124 | PP_1288 | Putative Glycosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | GDP-mannose 6-dehydrogenase; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity). | 0.471 |
PP_3142 | PP_2124 | PP_3142 | PP_2124 | Putative Sugar transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Putative Glycosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.679 |
PP_3142 | algA | PP_3142 | PP_1277 | Putative Sugar transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity). | 0.974 |
PP_3142 | algC | PP_3142 | PP_5288 | Putative Sugar transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Phosphomannomutase/phosphoglucomutase; The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for biofilm production (By similarity). | 0.694 |
PP_3142 | algD | PP_3142 | PP_1288 | Putative Sugar transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | GDP-mannose 6-dehydrogenase; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity). | 0.600 |
PP_3142 | cpsG | PP_3142 | PP_1777 | Putative Sugar transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Phosphomannomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars. | 0.674 |
PP_3142 | gmd | PP_3142 | PP_1799 | Putative Sugar transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | 0.969 |
algA | PP_2124 | PP_1277 | PP_2124 | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity). | Putative Glycosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.951 |
algA | PP_3142 | PP_1277 | PP_3142 | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity). | Putative Sugar transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.974 |
algA | algC | PP_1277 | PP_5288 | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity). | Phosphomannomutase/phosphoglucomutase; The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for biofilm production (By similarity). | 0.995 |
algA | algD | PP_1277 | PP_1288 | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity). | GDP-mannose 6-dehydrogenase; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity). | 0.996 |
algA | algF | PP_1277 | PP_1278 | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity). | Alginate biosynthesis protein AlgF; Together with AlgI and AlgJ, forms an inner membrane complex which probably interacts with the alginate polymerization-transport complex and adds acetyl groups at the O-2 and O-3 positions of mannuronate residues. Acetylation of alginate is important for the architecture of biofilms and increases the ability of alginate to act as a defense barrier (By similarity). | 0.966 |
algA | algI | PP_1277 | PP_1280 | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity). | Probable alginate O-acetylase AlgI; Together with AlgJ and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization-transport complex and adds acetyl groups at the O-2 and O-3 positions of mannuronate residues. Acetylation of alginate is important for the architecture of biofilms and increases the ability of alginate to act as a defense barrier (By similarity). | 0.962 |
algA | algJ | PP_1277 | PP_1279 | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity). | Probable alginate O-acetylase AlgJ; Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization-transport complex and adds acetyl groups at the O-2 and O-3 positions of mannuronate residues. Acetylation of alginate is important for the architecture of biofilms and increases the ability of alginate to act as a defense barrier (By similarity). | 0.953 |
algA | cpsG | PP_1277 | PP_1777 | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity). | Phosphomannomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars. | 0.987 |
algA | gmd | PP_1277 | PP_1799 | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity). | GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | 0.978 |
algA | pgi-I | PP_1277 | PP_1808 | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity). | Glucose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.950 |
algC | PP_3142 | PP_5288 | PP_3142 | Phosphomannomutase/phosphoglucomutase; The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for biofilm production (By similarity). | Putative Sugar transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.694 |