node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PP_1776 | alg8 | PP_1776 | PP_1287 | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Glycosyltransferase alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid. | 0.461 |
PP_1776 | algA | PP_1776 | PP_1277 | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity). | 0.924 |
PP_1776 | algD | PP_1776 | PP_1288 | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | GDP-mannose 6-dehydrogenase; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity). | 0.972 |
PP_1776 | algE | PP_1776 | PP_1284 | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Alginate production protein AlgE; Has non-porin-like, channel-forming properties and probably functions as an alginate permeability pore. | 0.430 |
PP_1776 | gmd | PP_1776 | PP_1799 | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | 0.980 |
alg44 | alg8 | PP_1286 | PP_1287 | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | Glycosyltransferase alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid. | 0.998 |
alg44 | algA | PP_1286 | PP_1277 | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity). | 0.917 |
alg44 | algD | PP_1286 | PP_1288 | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | GDP-mannose 6-dehydrogenase; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity). | 0.993 |
alg44 | algE | PP_1286 | PP_1284 | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | Alginate production protein AlgE; Has non-porin-like, channel-forming properties and probably functions as an alginate permeability pore. | 0.988 |
alg44 | algG | PP_1286 | PP_1283 | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | poly(beta-D-mannuronate) C5 epimerase; Catalyzes the epimerization of beta-D-mannuronate to alpha-L- guluronate during the synthesis of the linear polysaccharide alginate. In addition, is part of a periplasmic protein complex that protects alginate from degradation by AlgL by channeling the newly formed alginate polymer through a scaffold that transfers the alginate polymer through the periplasmic space to the outer membrane secretin AlgE. | 0.997 |
alg44 | algK | PP_1286 | PP_1285 | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | Alginate biosynthesis protein AlgK; May be involved in the polymerization of mannuronate to alginate. | 0.993 |
alg44 | algL | PP_1286 | PP_1281 | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | Alginate lyase; Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism. May serve to degrade mislocalized alginate that is trapped in the periplasmic space. | 0.984 |
alg44 | algX | PP_1286 | PP_1282 | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | Alginate biosynthesis protein AlgX; Plays two roles in the biosynthesis of the exopolysaccharide alginate: protects alginate from degradation as the polymer traverses the periplasm, and also plays a role in its O-acetylation. Probably has acetyltransferase activity in vivo (By similarity). | 0.990 |
alg8 | PP_1776 | PP_1287 | PP_1776 | Glycosyltransferase alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid. | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.461 |
alg8 | alg44 | PP_1287 | PP_1286 | Glycosyltransferase alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid. | Alginate biosynthesis protein Alg44; Required for alginate biosynthesis. | 0.998 |
alg8 | algA | PP_1287 | PP_1277 | Glycosyltransferase alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid. | Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity). | 0.934 |
alg8 | algD | PP_1287 | PP_1288 | Glycosyltransferase alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid. | GDP-mannose 6-dehydrogenase; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity). | 0.996 |
alg8 | algE | PP_1287 | PP_1284 | Glycosyltransferase alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid. | Alginate production protein AlgE; Has non-porin-like, channel-forming properties and probably functions as an alginate permeability pore. | 0.990 |
alg8 | algG | PP_1287 | PP_1283 | Glycosyltransferase alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid. | poly(beta-D-mannuronate) C5 epimerase; Catalyzes the epimerization of beta-D-mannuronate to alpha-L- guluronate during the synthesis of the linear polysaccharide alginate. In addition, is part of a periplasmic protein complex that protects alginate from degradation by AlgL by channeling the newly formed alginate polymer through a scaffold that transfers the alginate polymer through the periplasmic space to the outer membrane secretin AlgE. | 0.996 |
alg8 | algK | PP_1287 | PP_1285 | Glycosyltransferase alg8; Possibly a processive enzyme that polymerizes GDP-mannuronic acid. | Alginate biosynthesis protein AlgK; May be involved in the polymerization of mannuronate to alginate. | 0.997 |