STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
degSQuality control serine endoprotease DegS; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Proteinfate : Degradation of proteins, peptides, and glycopeptides. (402 aa)    
Predicted Functional Partners:
rseP
Regulatory intramembrane protein RIP zinc protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Regulatoryfunctions : Protein interactions.
 
  
 0.889
hldE
Heptose 7-phosphate kinase/heptose 1-phosphate adenylyltransferase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family.
     
 0.834
mucA
Sigma factor AlgU negative regulatory protein.
  
 
 0.801
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.648
ybgI
Putative metal-binding hydrolase-oxidase enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknown function.
  
    0.625
oprF
Outer membrane porin F.
    
 
 0.589
phoQ
Sensor protein; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription.
  
  
 0.580
PP_3761
Sensor histidine kinase/response regulator.
  
  
 0.554
ftsH
Integral membrane ATP-dependent zinc metallopeptidase; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 
 0.551
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.550
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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