STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
diaAFactor modulating bacterial replication archosome assembly; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (195 aa)    
Predicted Functional Partners:
hldE
Heptose 7-phosphate kinase/heptose 1-phosphate adenylyltransferase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family.
  
 0.999
gmhB
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate (beta-HBP) intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position. Belongs to the gmhB family.
  
 0.998
waaF
ADP-heptose:LPS heptosyltransferase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
 
  
 0.959
PP_1322
Putative Lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
    0.944
waaC
ADP-heptose:LPS heptosyltransferase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Cellenvelope : Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
 
  
 0.930
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
  
 0.846
waaA
3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
   
 0.831
kdsC
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.
  
  
 0.813
lpxB
Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.770
ydfG
3-hydroxy acid dehydrogenase, NADP-dependent / malonic semialdehyde reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Amino acids and amines.
   
 
 0.765
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.