STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdfAPutative multidrug efflux MFS transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Transport and binding proteins. (414 aa)    
Predicted Functional Partners:
emrB
Multidrug efflux transport system - permease subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transport and binding proteins; Belongs to the major facilitator superfamily.
  
   
 0.862
emrA
Multidrug efflux transport system - membrane fusion protein; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transport and binding proteins.
   
 
 0.790
norM
Probable multidrug resistance protein NorM; Multidrug efflux pump; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
     
 0.779
tolC
Agglutination protein.
  
  
 0.716
pvdT
Pyoverdine efflux carrier and ATP binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
   
 
 0.700
ttgR
Probable HTH-type transcriptional regulator TtgR; Probable regulatory protein for the ttgABC efflux pump operon. May function as a repressor (By similarity).
      
 0.647
mdeA
Methionine gamma-lyase; Function experimentally demonstrated in the studied strain; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
      
 0.603
oprN
Multidrug efflux RND outer membrane protein OprN.
   
  
 0.595
mexB
Multidrug resistance protein MexB.
    
 
 0.546
PP_1353
Homologs of previously reported genes of unknown function.
       0.495
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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