STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ttgRProbable HTH-type transcriptional regulator TtgR; Probable regulatory protein for the ttgABC efflux pump operon. May function as a repressor (By similarity). (210 aa)    
Predicted Functional Partners:
ttgB
Probable efflux pump membrane transporter TtgB; Probable membrane transporter component of the TtgABC efflux pump with unknown specificity; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  
 0.952
ttgA
Probable efflux pump periplasmic linker TtgA; Probable periplasmic linker protein component of the TtgABC efflux pump with unknown specificity; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
 0.936
ttgC
Probable efflux pump outer membrane protein TtgC; Probable outer membrane component of the TtgABC efflux pump with unknown specificity; Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
     
 0.833
mexB
Multidrug resistance protein MexB.
     
 0.810
lexA-II
Transcriptional repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
      
 0.765
lexA-I
Transcriptional repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
      
 0.751
rarA
DNA-dependent ATPase required for recombination; Function experimentally demonstrated in the studied strain; cell process; DNAmetabolism : DNA replication, recombination, and repair.
      
 0.700
norM
Probable multidrug resistance protein NorM; Multidrug efflux pump; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
     
 0.663
mdtC
Multidrug efflux transport system - membrane subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transport and binding proteins; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
     
 0.657
cusA
Probable copper efflux transporter, CzcA family; Function of homologous gene experimentally demonstrated in an other organism; transporter; Biologicalprocesses : Excrete; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
      
 0.634
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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