STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
PP_1389Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. (291 aa)    
Predicted Functional Partners:
gltA
Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the citrate synthase family.
 0.932
lldD
L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
   
 
 0.931
mdh
Putative malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
 0.929
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
    
 0.927
mqo-III
Malate:quinone oxidoreductase; Function of strongly homologous gene; enzyme; Energymetabolism : TCA cycle.
     
 0.915
maeB
Malic enzyme B; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.913
pykA
Pyruvate kinase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the pyruvate kinase family.
   
 
 0.911
ldhA
D-lactate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.911
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.911
ppsA
Phosphoenolpyruvate synthetase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
   
 
 0.908
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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