Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_14123-hydroxyisobutyryl-CoA hydrolase; Function of strongly homologous gene; enzyme. (368 aa)    
Predicted Functional Partners:
mmsB
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
 
 0.955
rsuA
Ribosomal small subunit pseudouridine synthase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family; Belongs to the pseudouridine synthase RsuA family.
     
 0.935
ung
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
     
 0.908
PP_0580
MaoC domain protein.
  
 0.882
PP_4817
MaoC domain protein.
  
 0.882
PP_4552
Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.878
bktB
Beta-ketothiolase BktB; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.735
PP_3358
hydroxycinnamoyl-CoA hydratase-lyase; Function of strongly homologous gene; enzyme; Biologicalprocesses : Scavenge (Catabolism); Belongs to the enoyl-CoA hydratase/isomerase family.
 
   0.688
pcaF-II
Beta-ketoadipyl CoA thiolase, beta component; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
  
 0.681
fadA
3-ketoacyl-CoA thiolase (thiolase I); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.673
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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