STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
PP_1430Putative periplasmic serine endoprotease DegP-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the peptidase S1C family. (492 aa)    
Predicted Functional Partners:
mucA
Sigma factor AlgU negative regulatory protein.
  
 
 0.884
lepB
Signal peptidase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Transport and binding proteins; Belongs to the peptidase S26 family.
 
   
 0.739
mucB
Sigma factor AlgU regulatory protein MucB.
  
  
 0.719
lepA
Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
 
  
 0.679
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
 0.650
rpoE
RNA polymerase sigma E factor; Function of homologous gene experimentally demonstrated in an other organism; factor; Transcription; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.611
PP_0725
Conserved hypothetical TPR repeat protein; Homologs of previously reported genes of unknown function.
 
  
 0.565
PP_3761
Sensor histidine kinase/response regulator.
  
  
 0.556
PP_2100
Two-component sensor protein; Function of homologous gene experimentally demonstrated in an other organism; receptor.
  
  
 0.529
rseP
Regulatory intramembrane protein RIP zinc protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Regulatoryfunctions : Protein interactions.
 
  
 0.523
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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