STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_1437Heavy metal sensor histidine kinase; Member of a two-component regulatory system. (460 aa)    
Predicted Functional Partners:
czcR-III
Response regulator; Function of strongly homologous gene; regulator; Biologicalprocesses : Control.
 0.996
copR-I
Transcriptional activator protein; Function experimentally demonstrated in the studied genus; regulator; Biologicalprocesses : Control.
 0.984
copR-II
Transcriptional activator protein; Function experimentally demonstrated in the studied genus; regulator; Biologicalprocesses : Control.
 0.983
PP_1922
Homologs of previously reported genes of unknown function.
   
  
 0.930
czcR-II
Response regulator; Function experimentally demonstrated in the studied genus; regulator; Biologicalprocesses : Control.
 
 0.848
czcR-I
Two component heavy metal response regulator; Function of strongly homologous gene; regulator; Biologicalprocesses : Control.
 
 0.847
colR
DNA-binding response regulator; Function of strongly homologous gene; regulator; Regulatory functions.
 
 0.842
gluQ
Glutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
   
  
 0.841
PP_2907
DNA-binding response regulator.
 
 0.832
PP_1651
Two-component response regulator; Function of strongly homologous gene; regulator; Regulatory functions.
 
 0.831
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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