Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_1437Heavy metal sensor histidine kinase; Member of a two-component regulatory system. (460 aa)    
Predicted Functional Partners:
czcR-III
Response regulator; Function of strongly homologous gene; regulator; Biologicalprocesses : Control.
 0.986
aroP-I
Aromatic amino acid transport protein; Function of homologous gene experimentally demonstrated in an other organism; transporter; Aminoacidbiosynthesis : Aromatic amino acid family.
      
 0.970
PP_1922
Homologs of previously reported genes of unknown function.
      
 0.951
czcR-I
Two component heavy metal response regulator; Function of strongly homologous gene; regulator; Biologicalprocesses : Control.
 0.947
czcR-II
Response regulator; Function experimentally demonstrated in the studied genus; regulator; Biologicalprocesses : Control.
 0.944
copR-I
Transcriptional activator protein; Function experimentally demonstrated in the studied genus; regulator; Biologicalprocesses : Control.
 0.944
copR-II
Transcriptional activator protein; Function experimentally demonstrated in the studied genus; regulator; Biologicalprocesses : Control.
 0.943
coq
2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
      
 0.895
gluQ
Glutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
   
  
 0.864
aroP-II
Aromatic amino acid transport protein; Function of homologous gene experimentally demonstrated in an other organism; transporter; Aminoacidbiosynthesis : Aromatic amino acid family.
      
 0.863
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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