Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
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nudLPutative NUDIX hydrolase with low 3-phosphohydroxypyruvate phosphatase activity; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Biologicalprocesses : Maintain. (199 aa)    
Predicted Functional Partners:
PP_1455
Homologs of previously reported genes of unknown function.
  
    0.810
PP_1452
MutT/nudix family protein.
 
  
 0.798
PP_1451
Homologs of previously reported genes of unknown function.
       0.730
PP_1454
Homologs of previously reported genes of unknown function.
  
    0.710
purT
Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.
  
  
 0.661
nudC
NADH pyrophosphatase.
 
   
 0.659
birA
Bifunctional biotin-[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
   
    0.618
nudJ
MutT/nudix family protein; Belongs to the Nudix hydrolase family. NudJ subfamily.
  
  
 0.602
nudF
ADP-ribose/sugar pyrophosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines, pyrimidines, nucleosides, and nucleotides.
   
  
 0.599
nudE
ADP-sugar pyrophosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Purines, pyrimidines, nucleosides, and nucleotides.
  
  
 0.595
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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