Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hicBHicB protein. (110 aa)    
Predicted Functional Partners:
PP_1480
Homologs of previously reported genes of unknown function.
 
   
 0.988
chpB
mRNA interferase; Function of homologous gene experimentally demonstrated in an other organism; factor; Regulatory functions.
  
  
 0.861
res
Conserved protein of unknown function; Toxic component of a type II toxin-antitoxin (TA) system. Expression in E.coli inhibits cell growth. In vivo it is probably neutralized by cognate antitoxin Xre; this has not been shown upon expression in E.coli. Probably depletes intracellular NAD(+) (By similarity); Belongs to the MbcT/ParT/Res family.
      
 0.861
mqsA
Antitoxin of the type II toxin-antitoxin MqsRA system and DNA-binding transcriptional repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator; Regulatory functions.
  
   
 0.838
PP_3900
Hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.786
xre
Conserved protein of unknown function; Probable antitoxin component of a type II toxin-antitoxin (TA) system. In vivo probably neutralizes the toxic effect of cognate toxin Res.
   
  
 0.743
hcpC-I
Hemolysin-coregulated protein; Function of strongly homologous gene; factor.
      
 0.656
hcpC-II
Hemolysin-coregulated protein; Function of strongly homologous gene; factor.
      
 0.656
PP_4530
Homologs of previously reported genes of unknown function.
  
     0.582
mqsR
Motility quorum-sensing regulator / GCU-specific mRNA interferase toxin; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription : Degradation of RNA.
      
 0.527
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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