Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_1480Homologs of previously reported genes of unknown function. (84 aa)    
Predicted Functional Partners:
hicB
HicB protein.
 
   
 0.988
PP_3900
Hypothetical protein; Homologs of previously reported genes of unknown function.
  
   
 0.907
mqsA
Antitoxin of the type II toxin-antitoxin MqsRA system and DNA-binding transcriptional repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator; Regulatory functions.
  
   
 0.888
PP_3899
Conserved protein of unknown function, hicB family; Homologs of previously reported genes of unknown function; Unknown function.
 
   
 0.884
PP_4530
Homologs of previously reported genes of unknown function.
  
   
 0.874
PP_0274
Putative transcriptional regulator containing HTH domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions.
  
   
 0.868
res
Conserved protein of unknown function; Toxic component of a type II toxin-antitoxin (TA) system. Expression in E.coli inhibits cell growth. In vivo it is probably neutralized by cognate antitoxin Xre; this has not been shown upon expression in E.coli. Probably depletes intracellular NAD(+) (By similarity); Belongs to the MbcT/ParT/Res family.
      
 0.854
PP_1586
Putative Killer protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.836
PP_0770
PemI-like protein.
  
   
 0.826
xre
Conserved protein of unknown function; Probable antitoxin component of a type II toxin-antitoxin (TA) system. In vivo probably neutralizes the toxic effect of cognate toxin Res.
      
 0.815
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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