Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_1489CheW domain protein. (168 aa)    
Predicted Functional Partners:
PP_1492
Sensor histidine kinase/response regulator.
 0.999
PP_1488
Methyl-accepting chemotaxis transducer.
 
 0.998
PP_1491
CheW domain protein.
 
  
 0.998
cheBC
Chemotaxis response regulator protein-glutamate methylesterase of group 3 operon; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
 
 
 0.997
PP_1494
Response regulator/GGDEF domain protein.
 
 
 0.995
wspC
Probable biofilm formation methyltransferase WspC; Involved in biofilm formation.
  
 0.991
PP_4988
Signal transduction histidine kinase CheA/CheY-like receiver; Function of strongly homologous gene; enzyme; Signaltransduction : Two-component systems.
 
 
 0.955
cheA
Chemotaxis histidine kinase CheA.
 
 
 0.944
cheBA
Chemotaxis response regulator protein-glutamate methylesterase of group 1 operon; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
 
  
 0.877
mcpQ
Putative methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. McpQ recognizes specifically citrate and citrate/metal(2+) complexes. Binds citrate/metal(2+) complexes with higher affinity than free citrate, and mediates preferentially chemotaxis toward citrate/metal(2+) complexes.
 
 
 0.818
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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