STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PP_1504Homologs of previously reported genes of unknown function. (125 aa)    
Predicted Functional Partners:
PP_0357
ACT domain protein.
  
    0.778
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
       0.745
PP_4819
Homologs of previously reported genes of unknown function.
  
     0.671
PP_4987
Putative Chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
    0.667
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
       0.630
fimV
Putative motility protein fimV; Function experimentally demonstrated in the studied genus; membrane component; Cellularprocesses : Chemotaxis and motility.
  
     0.630
PP_5311
Putative signal transduction protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Signal transduction.
  
     0.626
PP_4642
Cyclic diguanosine monophosphate-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
  
    0.614
PP_1663
Homologs of previously reported genes of unknown function.
  
    0.604
PP_1666
Homologs of previously reported genes of unknown function.
  
     0.603
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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