Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rlmAA23S rRNA m1G745 methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Transcription : RNA processing. (270 aa)    
Predicted Functional Partners:
dapE
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
  
    0.934
PP_1523
Homologs of previously reported genes of unknown function.
  
    0.852
PP_1526
Putative Beta-(1-3)-glucosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.706
tcdA
tRNA threonylcarbamoyladenosine dehydratase (t(6)A37 dehydratase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Proteinsynthesis : tRNA and rRNA base modification.
       0.644
trxC
Thioredoxin 2.
 
 
 
 0.588
ftsI
Peptidoglycan DD transpeptidase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
 
  
 0.568
rlmF
Ribosomal RNA large subunit methyltransferase F; Specifically methylates the adenine in position 1618 of 23S rRNA.
 
  
 0.556
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (10%) [HD]