STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_1637Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (308 aa)    
Predicted Functional Partners:
cysNC
Sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
      
 0.845
cysG
Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
     
 0.837
cysD
Sulfate adenylyltransferase subunit 2.
      
 0.836
PP_2041
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.754
PP_2701
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.751
GbpR
Galactose-binding protein regulator; Function of strongly homologous gene; regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.724
PP_3179
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.719
PP_5599
Putative transcriptional regulator, LysR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions; Belongs to the LysR transcriptional regulatory family.
  
     0.715
pcaQ
Transcriptional regulator PcaQ; Belongs to the LysR transcriptional regulatory family.
  
    0.705
PP_1863
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
    0.701
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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