Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
yfgDPutative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Cellularprocesses : Detoxification. (117 aa)    
Predicted Functional Partners:
PP_1644
NAD(P)H dehydrogenase (quinone); Belongs to the WrbA family.
  
    0.904
PP_1643
Homologs of previously reported genes of unknown function.
     
 0.873
pyrD
Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
      0.863
arsH
ArsH protein.
  
  
 0.803
PP_2716
Arsenate reductase; Function of strongly homologous gene; enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
 
  
 0.785
PP_1232
Conserved exported protein of unknown function; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
 
  
 0.699
yffB
Putative glutathione-dependent thiol reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknown function; Belongs to the ArsC family.
  
  
 0.663
PP_1928
Arsenate reductase; Function of strongly homologous gene; enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
 
  
 0.631
PP_1646
Putative Thioredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.628
PP_0249
Homologs of previously reported genes of unknown function.
 
     0.601
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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