STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhAD-lactate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Energy metabolism; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (342 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.938
pykA
Pyruvate kinase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Anaerobic; Belongs to the pyruvate kinase family.
  
 0.927
gloB
Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
 
 0.923
lldD
L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
  
 
 0.923
ppsA
Phosphoenolpyruvate synthetase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.922
aceE
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.917
PP_0772
Metallo-beta-lactamase family protein.
  
 0.911
PP_1389
Oxaloacetate decarboxylase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
  
 0.911
maeB
Malic enzyme B; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.909
pycB
Pyruvate carboxylase subunit B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
    
 0.901
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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