STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfeS-IIHistidine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (458 aa)    
Predicted Functional Partners:
PP_1651
Two-component response regulator; Function of strongly homologous gene; regulator; Regulatory functions.
 
 0.996
PP_0534
Putative Transcriptional regulator PfeR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 0.984
pfeS-I
Histidine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 
0.908
cpxR
CpxR-Pasp DNA-binding transcriptional two-component system regulator; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transcription.
 
 
 0.817
PP_3454
Putative transcriptional regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Regulatory functions.
 
 
 0.817
PP_4503
DNA-binding response regulator.
 
 
 0.817
PP_1181
DNA-binding response regulator.
 
 
 0.809
PP_3484
Response regulator receiver protein.
 
   0.807
aruR
Transcriptional regulatory protein AruR.
 
 
 0.799
gltR-II
DNA-binding response regulator; Function of homologous gene experimentally demonstrated in an other organism; regulator.
 
 
 0.792
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.