STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fklB-IIFKBP-type peptidyl-prolyl cis-trans isomerase; Function of strongly homologous gene; enzyme; Proteinfate : Protein folding and stabilization. (250 aa)    
Predicted Functional Partners:
PP_4313
Putative peptidylprolyl isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
    
0.897
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.
    
 0.717
apaH
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
 0.625
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
   0.556
PP_1715
Homologs of previously reported genes of unknown function.
       0.488
ettA
ADP/ATP ratio sensor and inhibitor of translation; Function of homologous gene experimentally demonstrated in an other organism; receptor; Transport and binding proteins.
  
 
 0.435
pcaQ
Transcriptional regulator PcaQ; Belongs to the LysR transcriptional regulatory family.
       0.435
hscA
DnaK-like molecular chaperone specific for IscU; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
   
 0.429
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.429
PP_4849
Putative DnaK protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
 0.429
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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