Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prcTail-specific protease prc; Belongs to the peptidase S41A family. (704 aa)    
Predicted Functional Partners:
rseP
Regulatory intramembrane protein RIP zinc protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Regulatoryfunctions : Protein interactions.
 
  
 0.917
PP_0725
Conserved hypothetical TPR repeat protein; Homologs of previously reported genes of unknown function.
  
 
 0.779
PP_1720
Alcohol dehydrogenase, zinc-containing.
       0.754
PP_2192
Putative RNA polymerase sigma-70 factor, ECF subfamily/transmembrane sensor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the sigma-70 factor family.
     
 0.741
degS
Quality control serine endoprotease DegS; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Proteinfate : Degradation of proteins, peptides, and glycopeptides.
 
  
 0.669
mucA
Sigma factor AlgU negative regulatory protein.
      
 0.668
sohB
Putative inner membrane peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Proteinfate : Degradation of proteins, peptides, and glycopeptides.
  
  
 0.636
algC
Phosphomannomutase/phosphoglucomutase; The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for biofilm production (By similarity).
   
 
 0.577
mucB
Sigma factor AlgU regulatory protein MucB.
      
 0.548
fecA
Outer membrane ferric citrate porin; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Porins.
      
 0.526
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: low (10%) [HD]