Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PP_1756Homologs of previously reported genes of unknown function. (174 aa)    
Predicted Functional Partners:
bolA
DNA-binding transcriptional dual regulator; Function of homologous gene experimentally demonstrated in an other organism; regulator; Regulatory functions; Belongs to the BolA/IbaG family.
  
    0.933
fumC-II
Fumarate hydratase (class 2); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
       0.744
PP_1759
Homologs of previously reported genes of unknown function.
 
     0.739
PP_1760
ABC transporter, ATP-binding protein.
 
     0.728
PP_1758
Putative sulfurtransferase containing rhodanese-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Unknownfunction : Enzymes of unknown specificity; Belongs to the UPF0176 family.
       0.725
PP_3397
Homologs of previously reported genes of unknown function.
  
    0.703
algX
Alginate biosynthesis protein AlgX; Plays two roles in the biosynthesis of the exopolysaccharide alginate: protects alginate from degradation as the polymer traverses the periplasm, and also plays a role in its O-acetylation. Probably has acetyltransferase activity in vivo (By similarity).
  
     0.678
yegE
Diguanylate cyclase with phosphodiesterase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Proteinfate : Protein modification and repair.
     
 0.628
PP_0149
Homologs of previously reported genes of unknown function.
  
     0.627
PP_0521
Homologs of previously reported genes of unknown function.
  
     0.602
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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