| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PP_0662 | PP_2533 | PP_0662 | PP_2533 | Putative Threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | D-isomer specific 2-hydroxyacid dehydrogenase family protein. | 0.410 |
| PP_0662 | aroA | PP_0662 | PP_1770 | Putative Threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.423 |
| PP_0662 | pdxA | PP_0662 | PP_0402 | Putative Threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.902 |
| PP_0662 | pheA | PP_0662 | PP_1769 | Putative Threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Chorismate mutase/Prephenate dehydratase; Function of strongly homologous gene; enzyme. | 0.480 |
| PP_0662 | serA | PP_0662 | PP_5155 | Putative Threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase; Function experimentally demonstrated in the studied species; enzyme; Aminoacidbiosynthesis : Serine family; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.410 |
| PP_0662 | serC | PP_0662 | PP_1768 | Putative Threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.940 |
| PP_0662 | thrC | PP_0662 | PP_1471 | Putative Threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Threonine synthase. | 0.906 |
| PP_2533 | PP_0662 | PP_2533 | PP_0662 | D-isomer specific 2-hydroxyacid dehydrogenase family protein. | Putative Threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.410 |
| PP_2533 | serA | PP_2533 | PP_5155 | D-isomer specific 2-hydroxyacid dehydrogenase family protein. | D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase; Function experimentally demonstrated in the studied species; enzyme; Aminoacidbiosynthesis : Serine family; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.907 |
| PP_2533 | serC | PP_2533 | PP_1768 | D-isomer specific 2-hydroxyacid dehydrogenase family protein. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.967 |
| PP_2533 | thrC | PP_2533 | PP_1471 | D-isomer specific 2-hydroxyacid dehydrogenase family protein. | Threonine synthase. | 0.410 |
| aroA | PP_0662 | PP_1770 | PP_0662 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Putative Threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.423 |
| aroA | pheA | PP_1770 | PP_1769 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate mutase/Prephenate dehydratase; Function of strongly homologous gene; enzyme. | 0.999 |
| aroA | serB | PP_1770 | PP_4909 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Phosphoserine phosphatase; Function experimentally demonstrated in the studied genus; enzyme; Aminoacidbiosynthesis : Serine family. | 0.429 |
| aroA | serC | PP_1770 | PP_1768 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.977 |
| aroA | thrC | PP_1770 | PP_1471 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Threonine synthase. | 0.423 |
| cysK | serC | PP_4571 | PP_1768 | Cysteine synthase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Serine family; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.924 |
| pdxA | PP_0662 | PP_0402 | PP_0662 | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | Putative Threonine synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.902 |
| pdxA | pdxB | PP_0402 | PP_2117 | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. | 0.896 |
| pdxA | serC | PP_0402 | PP_1768 | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.950 |
