STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_1776Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. (480 aa)    
Predicted Functional Partners:
cpsG
Phosphomannomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Sugars.
 
 0.992
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
 
 
 0.980
algD
GDP-mannose 6-dehydrogenase; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity).
 
 
 0.972
PP_3142
Putative Sugar transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.972
algC
Phosphomannomutase/phosphoglucomutase; The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for biofilm production (By similarity).
 
 0.970
pgi-I
Glucose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.950
PP_2124
Putative Glycosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.950
pgi-II
Glucose-6-phosphate isomerase; Function of strongly homologous gene; enzyme.
  
 
 0.950
fbp
Fructose-1,6-bisphosphatase, class 1; Function of strongly homologous gene; enzyme; Energymetabolism : Glycolysis/gluconeogenesis.
   
 0.933
algA
Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity).
 
  
 
0.924
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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